EENdb - TALEN/ZFN
Search TALENs/ZFNs targeting the sequence:
- >=3 nt (recommend >=6 nt), 5'->3', any strand
- use [...] for alternate nucleotides; N = [ACGT]
Search TALENs/ZFNs targeting the gene(s):
- <=10 symbols or IDs (currently Ensembl ID only)
- symbols are variable in publications and databases
Search EENs by first reported reference:
- <=10 PubMed IDs or surnames of 1st authors.

EEN Search Result
ZFN targeting sequences from mouse (Mus musculus): 16 ZFN records match.
(Click on ID to see details)


ZFN IDWhole SiteSpecies & LocusZFP Domain L.ZFP Domain R.LinkerFokIConstruc.Modif.Ref.Effic.
ZN0004 cTGACTCCTGatgttgattTTGGGAGAAc
gACTGAGGACtacaactaaAACCCTCTTg
    3F+[9]+3F
mouse, Cftr G ZP10008 ZP10007 TG(G4S)3 WT MA 16084494 R
ZN0005 gTTCCCCTTCaaagggGTGGATGACc
cAAGGGGAAGtttcccCACCTACTGg
    3F+[6]+3F
mouse, Tyr G ZP10010 ZP10009 TG WT MA 16084494 R
ZN0076 aGACATCCAGTTGgctcgCCGGATACGGGGa
tCTGTAGGTCAACcgagcGGCCTATGCCCCt
    4F+[5]+4F
mouse, H3f3b G ZP10498 ZP10499 LRGS EL+KK Sangamo HR 20211137 R
ZN0081 gGCCATCAGCCCTgttcttGGACTGTCAGCTGGTa
cCGGTAGTCGGGAcaagaaCCTGACAGTCGACCAt
    4F+[6]+5F
mouse, Abcb1a G ZP10553 ZP10554 LRGS WT Sangamo NHEJ 20628038 R
ZN0082 tTCCTTCCTCGCTGGCaggtgTGCGGGGCCTCGGGTc
aAGGAAGGAGCGACCGtccacACGCCCCGGAGCCCAg
    5F+[5]+5F
mouse, Jag1, intron-exon G ZPU0011 ZPU0012 LRGS WT Sangamo NHEJ 20628038 R
ZN0083 tGACTGCTCTCCGGATCcctgccACCACGGGCGCTGTGt
aCTGACGAGAGGCCTAGggacggTGGTGCCCGCGACACa
    (5F+1)+[6]+5F
mouse, Notch3 G ZPU0013 ZPU0014 LRGS WT Sangamo NHEJ 20628038 R
ZN0086 cTGCAACTCCAGTCTTTCTagaagaTGGGCGGGAGTCt
gACGTTGAGGTCAGAAAGAtcttctACCCGCCCTCAGa
    6F+[6]+4F
mouse, , intron G ZPU0015 ZPU0016 (N/A) (N/A) Sangamo NHEJ; HR 20686113 R
ZN0114 gGCGGCGTGCTCGcggtgcGGAGACCGGAAGg
cCGCCGCACGAGCgccacgCCTCTGGCCTTCc
    4F+[6]+4F
mouse, Thumpd3, 5'-UTR G ZP10699 ZP10700 TGEK WT MA(2F) NHEJ 21191366 R
ZN0136-T002 aAGGCAGGTGCTGTGTaagtacACTAAGGATGTGg
tTCCGTCCACGACACAttcatgTGATTCCTACACc
    5F+[6]+4F
mouse, (intergenic) G ZP10751-T002 ZP10752-T002 LRGS WT Sangamo NHEJ 21706032 R Low
ZN0086B cTGCAACTCCAGTCTTTCTagaagaTGGGCGGGAGTCt
gACGTTGAGGTCAGAAAGAtcttctACCCGCCCTCAGa
    6F+[6]+4F
mouse, G ZP10852 ZP10853 TGAAARA(-Q) WT, Sharkey-ELD+KKR MA NHEJ; HR 22169954 R
ZN0120B tGACCGCTTCTACcccaatGACTTGTGGGTGg
aCTGGCGAAGATGgggttaCTGAACACCCACc
    4F+[6]+4F
mouse, Cxcr4 G ZP10706 ZP10065 LRGS EL+KK Sangamo NHEJ 22273578 R
ZN0054-T002 gCACCAAAACTTCTCCtcgcacTACCGGGCCACCATTGTg
cGTGGTTTTGAAGAGGagcgtgATGGCCCGGTGGTAACAc
    6F+[6]+6F
mouse, Rab38 G ZP10462 ZP10463 LRGS EL+KK Sangamo NHEJ 22660928 R
ZN0054B gCACCAAAACTTCTCCtcgcacTACCGGGCCACCATTGTg
cGTGGTTTTGAAGAGGagcgtgATGGCCCGGTGGTAACAc
    5F+[6]+(2+5F)
mouse, Rab38 G ZPU0057 ZPU0058 (N/A) (N/A) (N/A) NHEJ 22660928 R
ZN0204 tATCTTTATGatgtgCTGTGAATGt
aTAGAAATACtacacGACACTTACa
    3F+[5]+3F
mouse, Ush1c [mutated] G ZP10890; ZP10891 ZP10888; ZP10889 LRGS WT MA Cleavage 22661463 R
ZN0205 tGCTGTGAATgtatcACCAGACCAt
aCGACACTTAcatagTGGTCTGGTa
    3F+[5]+3F
mouse, Ush1c [mutated] G ZP10893, ZP10894 ZP10892 LRGS WT MA Cleavage; HR 22661463 R
ZN0216 gCGCCCCTGCgcaacGTGGCAGGAa
cGCGGGGACGcgttgCACCGTCCTt
    3F+[5]+3F
mouse, G ZP10916 ZP10915 LRGS WT, EL+KK OPEN NHEJ; HR 22970113 R




Legends
Off-target or secondary target
EEN targeted same or overlapped site with another reported EEN
EEN reported with low or no activity
GSearch EENdb with this gene symbol
RSearch EENdb with this reference

©2012-2013  PKU Zebrafish Functional Genomics Group
School of Life Sciences, Peking University, Beijing, China
Reference of EENdb    Contact us