EENdb - TALEN/ZFN
Search TALENs/ZFNs targeting the sequence:
- >=3 nt (recommend >=6 nt), 5'->3', any strand
- use [...] for alternate nucleotides; N = [ACGT]
Search TALENs/ZFNs targeting the gene(s):
- <=10 symbols or IDs (currently Ensembl ID only)
- symbols are variable in publications and databases
Search EENs by first reported reference:
- <=10 PubMed IDs or surnames of 1st authors.

EEN Search Result
EEN targeting gene with symbol containing 'intergenic': 10 ZFN, 3 TALEN, 0 CRISPR/Cas records match.
(Click on ID to see details)


TALEN IDWhole SiteSpecies & LocusRVDsFrameworkFokIConstruc.Modif.Ref.Effic.
TN0025-T002 tTCCACCCAGCCCTCAGTgctctgctgaggcAGGATGGGTGGCTGGAAa
aAGGTGGGTCGGGAGTCAcgagacgactccgTCCTACCCACCGACCTTt
    17+[13]+17
human, [intergenic] C +63 ELD+KKR (N/A) NHEJ 21738127 R
TN0025-T003 cCCCCTCCACCCCAAAAAt...aAATATGAGTTATAGAAAa
gGGGGAGGTGGGGTTTTTa...tTTATACTCAATATCTTTt
    17+[24]+17
human, [intergenic] C +63 ELD+KKR (N/A) NHEJ 21738127 R
TN0032-T002 tTCCTGACCAGCTCCAAgcataaaagcatAACAGTAGAAAATTGAt
aAGGACTGGTCGAGGTTcgtattttcgtaTTGTCATCTTTTAACTa
    16+[12]+16
rat, [intergenic] +63 ELD+KKR (N/A) NHEJ 21822240 R



ZFN IDWhole SiteSpecies & LocusZFP Domain L.ZFP Domain R.LinkerFokIConstruc.Modif.Ref.Effic.
ZN0012 aACCCACTCCaagcttGGGGTGGCTt
tTGGGTGAGGttcgaaCCCCACCGAa
    3F+[6]+3F
worm, (intergenic) G ZP10027 ZP10026 QNKK WT MA NHEJ 17060623 R
ZN0017-T002 aTCCCACCCGagtcctGCAGGTGTGt
tAGGGTGGGCtcaggaCGTCCACACa
    3F+[6]+3F
zebrafish, (intergenic) G C ZP10047-T002 ZP10046-T002 TGGS D+R, EL+KK PRS NHEJ 20843781 R Low
ZN0017-T004 aCACACCTTCacagacGTGGGGGGAa
tGTGTGGAAGtgtctgCACCCCCCTt
    3F+[6]+3F
zebrafish, (intergenic) G C ZP10046 ZP10047-T004 TGGS D+R, EL+KK PRS NHEJ 20843781 R Low
ZN0017-T006 aACCCACCGAgatacGCGGGTGTGt
tTGGGTGGCTctatgCGCCCACACa
    3F+[5]+3F
zebrafish, (intergenic) G C ZP10047-T006 ZP10046-T004 TGGS D+R, EL+KK PRS NHEJ 20843781 R Low
ZN0017-T010 cTCCCACCCAggaagtGATGGTGAGt
gAGGGTGGGTccttcaCTACCACTCa
    3F+[6]+3F
zebrafish, (intergenic) G C ZP10047-T010 ZP10046-T008 TGGS D+R, EL+KK PRS NHEJ 20843781 R Low
ZN0017-T015 cACCCACCCActactGAGGGTGAGc
gTGGGTGGGTgatgaCTCCCACTCg
    3F+[5]+3F
zebrafish, (intergenic) G C ZP10047-T015 ZP10046-T013 TGGS D+R, EL+KK PRS NHEJ 20843781 R Low
ZN0017-T016 tCACACCTCCaattaGAGGCGGGAt
aGTGTGGAGGttaatCTCCGCCCTa
    3F+[5]+3F
zebrafish, (intergenic) G C ZP10046-T012 ZP10047-T016 TGGS D+R, EL+KK PRS NHEJ 20843781 R Low
ZN0119-T003 tATGGCATTGCCGTGAgttgcgCTATAGGTTGCAGATg
aTACCGTAACGGCACTcaacgcGATATCCAACGTCTAc
    5F+[6]+5F
pig, (intergenic) G ZPU0021-T003 ZPU0023-T003 LRGS EL+KK Sangamo NHEJ 21502977 R
ZN0120-T003 cCACCTACTTGTCttgtgtGTTGAAGCAGACa
gGTGGATGAACAGaacacaCAACTTCGTCTGt
    4F+[6]+4F
human, (intergenic) G C ZP10715-T003 ZP10716-T003 LRGS EL+KK Sangamo NHEJ 21533216 R Low
ZN0136-T002 aAGGCAGGTGCTGTGTaagtacACTAAGGATGTGg
tTCCGTCCACGACACAttcatgTGATTCCTACACc
    5F+[6]+4F
mouse, (intergenic) G ZP10751-T002 ZP10752-T002 LRGS WT Sangamo NHEJ 21706032 R Low




Legends
Off-target or secondary target
EEN targeted same or overlapped site with another reported EEN
EEN reported with low or no activity
GSearch EENdb with this gene symbol
RSearch EENdb with this reference

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