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TN0108
IDTN0108
Type / formTALEN, dimer. (T-D)
More about TALEN forms
Target Full sitetCGGCGCATGAAGGAGGTactcctcattttcgttCTCTCTCTCTGTGCCCCa
aGCCGCGTACTTCCTCCAtgaggagtaaaagcaaGAGAGAGAGACACGGGGt
LengthLeft+[Spacer]+Right: 17+[16]+17
Speiceshuman (Homo sapiens)
List EENs targeting genome of human
Gene / LocusNTRK1 G
Location to genearound ATG
TALENs Left site & RVDs
HD NN NN HD NN HD NI NG NN NI NI NN NN NI NN NN NG
  C  G  G  C  G  C  A  T  G  A  A  G  G  A  G  G  T  
Right site & RVDs
NN NN NN NN HD NI HD NI NN NI NN NI NN NI NN NI NN
  G  G  G  G  C  A  C  A  G  A  G  A  G  A  G  A  G  
TALEN framework
& linker peptide
+63
More about TALEN frameworks & linker pepetides
FokI variantWT
List EENs with FokI variants WT   More about FokI variants
Construction methodFLASH
List EENs constructed by FLASH   More about TALE construction methods
Effectiveness
(first reported)
Genome modification
method

More about modification methods
Efficiency- (see ref.), mismatch-detection nuclease assay (T7E1).
More about efficiency detection methods
Heritability
Specificity
Comments
Reference (first reported)Reyon et al., Nat Biotechnol., 2012 (22484455 R)
External database
& resource




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