EENdb - TALEN/ZFN  >  TALEN detail
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TN0103
IDTN0103
Type / formTALEN, dimer. (T-D)
More about TALEN forms
Target Full sitetCCCGCAGGGAGCGGACAtggactacgactcgtaCCAGCACTATTTCTACGa
aGGGCGTCCCTCGCCTGTacctgatgctgagcatGGTCGTGATAAAGATGCt
LengthLeft+[Spacer]+Right: 17+[16]+17
Speiceshuman (Homo sapiens)
List EENs targeting genome of human
Gene / LocusMYCL1 G
Location to genearound ATG
TALENs Left site & RVDs
HD HD HD NN HD NI NN NN NN NI NN HD NN NN NI HD NI
  C  C  C  G  C  A  G  G  G  A  G  C  G  G  A  C  A  
Right site & RVDs
HD NN NG NI NN NI NI NI NG NI NN NG NN HD NG NN NN
  C  G  T  A  G  A  A  A  T  A  G  T  G  C  T  G  G  
TALEN framework
& linker peptide
+63
More about TALEN frameworks & linker pepetides
FokI variantWT
List EENs with FokI variants WT   More about FokI variants
Construction methodFLASH
List EENs constructed by FLASH   More about TALE construction methods
Effectiveness
(first reported)
Genome modification
method
NHEJ
More about modification methods
Efficiency(see ref.), mismatch-detection nuclease assay (T7E1).
More about efficiency detection methods
Heritability
Specificity
Comments
Reference (first reported)Reyon et al., Nat Biotechnol., 2012 (22484455 R)
External database
& resource
Addgene 36715+36716




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