EENdb - TALEN/ZFN  >  TALEN detail
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TN0072
IDTN0072
Type / formTALEN, dimer. (T-D)
More about TALEN forms
Target Full sitetGCCCCGGCATGGCGACAccggacgcggggctcccTGGGGCTGAGGGCGTGGa
aCGGGGCCGTACCGCTGTggcctgcgccccgagggACCCCGACTCCCGCACCt
LengthLeft+[Spacer]+Right: 17+[17]+17
Speiceshuman (Homo sapiens)
List EENs targeting genome of human
Gene / LocusFANCE G
Location to genearound ATG
TALENs Left site & RVDs
NN HD HD HD HD NN NN HD NI NG NN NN HD NN NI HD NI
  G  C  C  C  C  G  G  C  A  T  G  G  C  G  A  C  A  
Right site & RVDs
HD HD NI HD NN HD HD HD NG HD NI NN HD HD HD HD NI
  C  C  A  C  G  C  C  C  T  C  A  G  C  C  C  C  A  
TALEN framework
& linker peptide
+63
More about TALEN frameworks & linker pepetides
FokI variantWT
List EENs with FokI variants WT   More about FokI variants
Construction methodFLASH
List EENs constructed by FLASH   More about TALE construction methods
Effectiveness
(first reported)
Genome modification
method

More about modification methods
Efficiency- (see ref.), mismatch-detection nuclease assay (T7E1).
More about efficiency detection methods
Heritability
Specificity
Comments
Reference (first reported)Reyon et al., Nat Biotechnol., 2012 (22484455 R)
External database
& resource




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