EENdb - TALEN/ZFN  >  TALEN detail
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TN0053
IDTN0053
Type / formTALEN, dimer. (T-D)
More about TALEN forms
Target Full sitetCTGCAATAAAAAATGGCctccaacaaaactacaTTGGTAAGTTAATGAAAa
aGACGTTATTTTTTACCGgaggttgttttgatgtAACCATTCAATTACTTTt
LengthLeft+[Spacer]+Right: 17+[16]+17
Speiceshuman (Homo sapiens)
List EENs targeting genome of human
Gene / LocusCBX3 G
Location to genearound ATG
TALENs Left site & RVDs
HD NG NN HD NI NI NG NI NI NI NI NI NI NG NN NN HD
  C  T  G  C  A  A  T  A  A  A  A  A  A  T  G  G  C  
Right site & RVDs
NG NG NG HD NI NG NG NI NI HD NG NG NI HD HD NI NI
  T  T  T  C  A  T  T  A  A  C  T  T  A  C  C  A  A  
TALEN framework
& linker peptide
+63
More about TALEN frameworks & linker pepetides
FokI variantWT
List EENs with FokI variants WT   More about FokI variants
Construction methodFLASH
List EENs constructed by FLASH   More about TALE construction methods
Effectiveness
(first reported)
Genome modification
method
NHEJ
More about modification methods
Efficiency(see ref.), mismatch-detection nuclease assay (T7E1).
More about efficiency detection methods
Heritability
Specificity
Comments
Reference (first reported)Reyon et al., Nat Biotechnol., 2012 (22484455 R)
External database
& resource
Addgene 36771+36772




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