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TN0047
IDTN0047
Type / formTALEN, dimer. (T-D)
More about TALEN forms
Target Full sitetCCCTCACCATGAGTAGCgctatgttggtgacttGCCTCCCGGACCCCAGCa
aGGGAGTGGTACTCATCGcgatacaaccactgaaCGGAGGGCCTGGGGTCGt
LengthLeft+[Spacer]+Right: 17+[16]+17
Speiceshuman (Homo sapiens)
List EENs targeting genome of human
Gene / LocusAXIN2 G
Location to genearound ATG
TALENs Left site & RVDs
HD HD HD NG HD NI HD HD NI NG NN NI NN NG NI NN HD
  C  C  C  T  C  A  C  C  A  T  G  A  G  T  A  G  C  
Right site & RVDs
NN HD NG NN NN NN NN NG HD HD NN NN NN NI NN NN HD
  G  C  T  G  G  G  G  T  C  C  G  G  G  A  G  G  C  
TALEN framework
& linker peptide
+63
More about TALEN frameworks & linker pepetides
FokI variantWT
List EENs with FokI variants WT   More about FokI variants
Construction methodFLASH
List EENs constructed by FLASH   More about TALE construction methods
Effectiveness
(first reported)
Genome modification
method
NHEJ
More about modification methods
Efficiency(see ref.), mismatch-detection nuclease assay (T7E1).
More about efficiency detection methods
Heritability
Specificity
Comments
Reference (first reported)Reyon et al., Nat Biotechnol., 2012 (22484455 R)
External database
& resource
Addgene 36663+36664




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