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TN0037
IDTN0037
Type / formTALEN, dimer. (T-D)
More about TALEN forms
Target Full sitetGCATCAACCCCATCATCtatgcctttgtcGGGGAGAAGTTCAGAAACTa
aCGTAGTTGGGGTAGTAGatacggaaacagCCCCTCTTCAAGTCTTTGAt
LengthLeft+[Spacer]+Right: 17+[12]+19
Speiceshuman (Homo sapiens)
List EENs targeting genome of human
Gene / LocusCCR5 G
Location to geneexon
TALENs Left site & RVDs
(RVDs unknown)
  G  C  A  T  C  A  A  C  C  C  C  A  T  C  A  T  C  
Right site & RVDs
(RVDs unknown)
  A  G  T  T  T  C  T  G  A  A  C  T  T  C  T  C  C  C  C  
TALEN framework
& linker peptide
(N/A)
More about TALEN frameworks & linker pepetides
FokI variant(N/A)
More about FokI variants
Construction method(N/A)
More about TALE construction methods
Effectiveness
(first reported)
Genome modification
method
NHEJ
More about modification methods
Efficiency2.8-3.1% (unsorted cell, see ref.), mismatch-detection nuclease assay (T7E1) & reporter gene correction assay.
More about efficiency detection methods
Heritability
Specificity
Comments
Reference (first reported)Kim et al., Nat Methods., 2011 (21983922 R)
External database
& resource




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