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TN0012
IDTN0012
Type / formTALEN, dimer. (T-D)
More about TALEN forms
Target Full sitetGGCACCATTAAAGAAAATATCATctttggtgtttcctatgatgaatatAGATACAGAAGCGTCATCAAAGCATGCCa
aCCGTGGTAATTTCTTTTATAGTAgaaaccacaaaggatactacttataTCTATGTCTTCGCAGTAGTTTCGTACGGt
LengthLeft+[Spacer]+Right: 23+[25]+28
Speiceshuman (Homo sapiens)
List EENs targeting genome of human
Gene / LocusCFTR G
Location to geneexon
TALENs Left site & RVDs
NN NN HD NI HD HD NI NG NG NI NI NI NN NI NI NI NI NG NI NG HD NI NG
  G  G  C  A  C  C  A  T  T  A  A  A  G  A  A  A  A  T  A  T  C  A  T  
Right site & RVDs
NN NN HD NI NG NN HD NG NG NG NN NI NG NN NI HD NN HD NG NG HD NG NN NG NI NG HD NG
  G  G  C  A  T  G  C  T  T  T  G  A  T  G  A  C  G  C  T  T  C  T  G  T  A  T  C  T  
TALEN framework
& linker peptide
+231 PthXo1
More about TALEN frameworks & linker pepetides
FokI variantWT
List EENs with FokI variants WT   More about FokI variants
Construction methodGG(V&B)
List EENs constructed by GG / V / B /    More about TALE construction methods
Effectiveness
(first reported)
Genome modification
method
(Weak)
More about modification methods
EfficiencyWeak, SSA assay, in yeast.
More about efficiency detection methods
Heritability
Specificity
Comments"CFTR B".
Reference (first reported)Cermak et al., Nucleic Acids Res., 2011 (21493687 R)
External database
& resource




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