EENdb - TALEN/ZFN > Chromosome View

EENs targeting human Chromosome 3

10 MbTALENsZFNsCRISPR/CasCurrently centered EEN (TN0003)


EEN IDSpecies & LocusRef.LocationLocation detailDistanceEffic.NotesCentering
TN0135 human, VHL, ATG G 22484455 R 10,183,541 3:10183515-10183567:+ -36.2 Mb C
TN0137 human, XPC, ATG G 22484455 R 14,220,057 3:14220030-14220085:- -32.2 Mb C
TN0131 human, TGFBR2 G 22484455 R 30,648,407 3:30648381-30648434:+ -15.8 Mb No C
ZN0071 human, CCR2/CCR5, 5'-up G 19952142 R 31,332,037 3:31332021-31332053:+ -15.1 Mb Multi-mappingC
TN0099 human, MLH1, ATG G 22484455 R 37,035,053 3:37035027-37035079:+ -9.4 Mb C
TN0061 human, CTNNB1, ATG G 22484455 R 41,265,572 3:41265547-41265598:+ -5.1 Mb C
ZN0070 human, CCR2/CCR5, 5'-up G 19952142 R 45,579,331 3:45579315-45579347:+ -835.2 kb C
ZN0069 human, CCR2/CCR5, 5'-up G 19952142 R 45,633,101 3:45633085-45633117:+ -781.5 kb C
ZN0068 human, CCR2/CCR5, 5'-up G 19952142 R 46,138,313 3:46138297-46138329:+ -276.3 kb C
ZN0067 human, CCR2/CCR5, 5'-up G 19952142 R 46,171,100 3:46171084-46171116:+ -243.5 kb C
ZN0066 human, CCR2/CCR5, 5'-up G 19952142 R 46,184,571 3:46184555-46184587:+ -230.0 kb C
ZN0065 human, CCR2/CCR5, 5'-up G 19952142 R 46,381,817 3:46381801-46381833:+ -32.7 kb Multi-mappingC
TN0031-T002 human, CCR2 G 21813459 R 46,399,215 3:46399189-46399242:+ -15.4 kb Low C
ZN0019-T002 human, CCR2 G 18587387 R 46,399,219 3:46399204-46399235:+ -15.3 kb C
ZN0046 human, CCR5/CCR2 G 19470664 R 46,399,468 3:46399452-46399484:+ -15.1 kb Multi-sitesC
ZN0047 human, CCR5 G 19470664 R 46,399,484 3:46399471-46399497:+ -15.1 kb C
ZN0048 human, CCR5/CCR2 G 19470664 R 46,399,489 3:46399475-46399504:+ -15.1 kb Multi-sitesC
ZN0050-T002 human, CCR2 G 19470664 R 46,399,937 3:46399922-46399953:+ -14.6 kb Low C
ZN0043 human, CCR5 G 19470664 R 46,414,427 3:46414411-46414443:+ -139 bp C
TN0031 human, CCR5 G 21813459 R 46,414,554 3:46414528-46414581:+ -12 bp Multi-mappingC
ZN0019 human, CCR5 G 18587387 R 46,414,558 3:46414543-46414574:+ -8 bp C
TN0003 human, CCR5 G 21179091 R 46,414,566 3:46414539-46414593:+ 0 (Centered)
ZN0006 human, CCR5 G 16084494 R 46,414,655 3:46414639-46414671:+ +89 bp C
ZN0055 human, CCR5 G 19635463 R 46,414,655 3:46414636-46414674:+ +89 bp C
ZN0044 human, CCR5 G 19470664 R 46,414,663 3:46414647-46414679:+ +97 bp C
ZN0045 human, CCR5/CCR2 G 19470664 R 46,414,755 3:46414741-46414769:+ +189 bp C
ZN0046 human, CCR5/CCR2 G 19470664 R 46,414,807 3:46414791-46414823:+ +241 bp Multi-sitesC
ZN0048 human, CCR5/CCR2 G 19470664 R 46,414,828 3:46414814-46414843:+ +262 bp Multi-sitesC
TN0002 human, CCR5 G 21179091 R 46,414,940 3:46414912-46414969:+ +374 bp C
ZN0056 human, CCR5 G 19635463 R 46,414,944 3:46414928-46414960:+ +378 bp C
ZN0050 human, CCR5 G 19470664 R 46,415,288 3:46415272-46415304:+ +722 bp C
TN0037 human, CCR5 G 21983922 R 46,415,289 3:46415264-46415314:+ +723 bp Multi-mappingC
ZN0084 human, RHO G 20671268 R 129,251,387 3:129251374-129251400:+ +82.8 Mb C
TN0049 human, BCL6, ATG G 22484455 R 187,451,474 3:187451448-187451500:- +141.0 Mb C



Legends
Currently centered EEN
Multiple designed target site of the centered EEN
EEN reported with low or no activity
123 bpEEN with a distance <1 kb to the centered EEN
-45.6 kbEEN with a distance 1 kb - 1 Mb to the centered EEN
78.9 MbEEN with a distance >1 Mb to the centered EEN
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